Best Western Santa Fe

4600 I-40 E, Amarillo, TX 79103-6200
Phone: +1 806-372-1885   |   Fax: 806/372-5384   |   56 Rooms
Check Out Time: 11:00 AM   |   Check In: 2:00 PM   |   Online Reservations

Business at Bell Helicopter and Pantex are just a couple of reasons many guests choose to stay at our conveniently located Amarillo hotel.

If you're in town for the Big Texan Steak Ranch, it's just a short drive away from our hotel in Amarillo, TX. Whether you're here for business or leisure, depend on us to provide you with the southern hospitality you deserve. Rick Husband International Airport is nearby, only three and a half miles away, so it's easy to catch an early or connecting flight. Adjoining rooms are available too, so families or groups can stay connected while on vacation.

Our pet-friendly Amarillo, TX hotel offers a free, full hot breakfast that includes waffles and cereal, yogurt, pastries, fruits and breakfast breads. Complete the most important meal of the day with cups of chilled juice or 100% Arabica coffee. The Palo Duro Canyon is nearby so to really enjoy a full day of exploration, a hearty breakfast is in order.

Spend your trip visiting Wonderland Park, the American Quarter Horse Museum or the Amarillo Zoo. Cadillac Ranch and the Route 66 Motor Speedway are also popular attractions. Golf is a popular activity in the area as well. There are endless things to do near our Amarillo hotel, so start planning your itinerary now. Our friendly staff members are happy to offer tips and recommendations on places to eat, things to do and sights to see, too.

A number of our Amarillo hotel guests are in town for business with Tyson, Bell Helicopter and Pantex. With the Amarillo Air Force Base (AFB) nearby, we also welcome service men and women along with their loved ones to our property. Our superior location makes it easy to get around town and the value and amenities are unbeatable.

Book a quiet, cool room at the Best Western Santa Fe today for an easy, stress-free trip!


Hotel Amenities & Services

  • Wireless internet connection in public areas
  • Complimentary breakfast
  • Complimentary coffee in lobby
  • Complimentary full breakfast choice of breads, cereal, fruit, hot eggs, hot breakfast meat, other hot items, yogurt, juice, and coffee.Served 6:00 a.m. to 9:00 a.m.
  • Complimentary local and national newspaper
  • Complimentary passes to local fitness and spa center
  • Outdoor pool, heated, seasonal
  • Safe deposit box, available
  • Cold weather hook-ups
  • Free parking, outdoors
  • Express check out
  • Ice/vending machines
  • Photocopy services, available 24-hours
  • Fax services, available 24-hours
  • Inter corridor
  • Cable or satellite television
  • Free wireless Internet access available in public areas and all guest rooms
  • Business center
  • Printer available
  • Computer available
  • Dataports
  • Higher rates may apply for holidays/special events
  • Spacious lobby with sitting area and cable television
  • Facilities available for the physically challenged

Best Western Santa Fe

Take advantage of the savings and fun with this special offer available at the best western santa fe in Amarillo.

Best Western Santa Fe

Conveniently located, the best western santa fe in Amarillo, Texas is shown on the map. Detailed driving directions from popular points or nearby cities are listed below. For those with GPS, here you go:

Longitude: 35.191935  /  Latitude: -101.781925


Driving Directions to Hotel


From: The north or south. Take Interstate 40 east and Exit 72B (Grand Street) through the light past Bolton stop sign to the Best Western Santa Fe on your right.

From: The east. Take Interstate 40, take Exit 73 (Bolton, Eastern Avenue) turn left on Bolton to the service road and turn left on the service road to the Best Western Santa Fe.

From: The west. Take Interstate 40 Take Exit 73 (Eastern Avenue) proceed straight ahead on service road to the Best Western Santa Fe.

Best Western Santa Fe

We care about the quality of your stay with us. Below are nearby attractions, shopping and restaurants that are popular with our guests. Listed locations are nearby with approximate distance listed where available.

Most Popular Area Attractions

Big Texan Steak Ranch

Established in 1960 by R.J. "Bob" Lee, the Big Texan Steak Ranch steakhous is located southeast of Amarillo on Interstate 40. Bob was inspired to build the restaurant after moving to the area from Kansas City and not finding a first-class Texas-style steakhouse.

The restaurant and its towering Cowboy sign, soon became a landmark along Route 66. As early as the 1960s, the restaurant began advertising its free, 72-ounce steak dinner to anyone who could finish it in one hour.

Travelers along I-40 in the Texas Panhandle will see the Big Texan Steakhouse billboards enticing them to the challenge.

While at the restaurant, be sure to browse the Big Texan gift shop to see the wonderful collection of Route 66 memorabilia, clothing, books, and toys.

Cadillac Ranch

TX Attractions

Cadillac Ranch

Set along Interstate 40 west of Amarillo, Cadillac Ranch is one of Texas' most unique attractions.

A group of 10 Cadillacs dating from 1948 to 1963 are half-way buried in the Texas Panhandle, each uniquely decorated by its visitors.

In 1974, Stanley Marsh III created this art exhibit near Historic Route 66 with help from "The Ant Farm" – a San Francisco art group. The majority of the Cadillacs were bought from junk yards at the time.

The public is encouraged to leave their mark on this ever-changing sculpture.

Comanche Trail Golf Course

Owned by the City of Amarillo, the Comanche Trail Golf Course is an ideal golf destination when visiting the panhandle region of Texas. 7,180 yards long from the championship tee boxes, and only 5,524 yards from the junior tee boxes, Comanche Trail Golf Course is fun, and challenging, for all levels of golfer. 

Before you tee off on the first hole at Comanche Trail Golf Course, head for the full length driving range and hit a bucket of ball to warm up. There are also two large practice greens for your short game – you don't want to miss a tap-in for birdie. 

Lake Meredith National Recreation Area

Be sure to visit Lake Meredith National Recreation Area on your next trek through Texas. Any spring or summer visit to the Lone Star State and its Panhandle region should include aquatic adventures on Lake Meredith. Only minutes west of Borger, and just north of Amarillo, Lake Meredith National Recreation Area is a sterling example of outdoor fun in Texas. 

Spanning a total of nearly 45,000 acres, Lake Meredith National Recreation Area is an ideal destination for spring or summer travelers. Lake Meredith, the centerpiece of the park, is roughly 10,000 acres in size, and is the result of the Sanford Dam being built. You can boat, fish, swim, and even hunt when you visit the Lake Meredith National Recreation Area. 

Palo Duro Canyon State Park

Palo Duro Canyon

Palo Duro Canyon State Park

The nation’s second largest canyon, Palo Duro Canyon is a Texas state park set in the Lone Star State’s panhandle region.

Stretching 120 miles long and spanning up to 20 miles long, Palo Duro Canyon State Park is a quick drive from northern Texas towns like Canyon, Clarendon, and Amarillo. Housing the Prairie Dog Town Fork Red River, Palo Duro Canyon is a major Texas tourist attraction.

Also known as the Grand Canyon of Texas, Palo Duro Canyon is a U.S. National Natural Landmark, and features plenty of activities for visitors.

Palo Duro visitors enjoy hikes to the iconic Lighthouse Peak, and a visit to the Palo Duro Canyon Interpretive Center – featuring a breathtaking view of the canyon.

Other Palo Canyon activities include picnics, bike trails, and horseback riding.

Rick Husband Amarillo International Airport

Encompassing 3,547 acres of the Texas Panhandle, the Rick Husband Amarillo International Airport (AMA) serves the city of Amarillo. Established as English Field in 1929, AMA had its first commercial flight through Transcontinental & Western Air. Once the adjacent Amarillo Air Force Base closed in 1968, the airport began using some of their buildings for terminal use.

In 2003, the Amarillo airport was named for NASA astronaut Rick Husband – an Amarillo native who died aboard the Space Shuttle Columbia. The airport was thus visited by the Space Shuttle Atlantis in 2007, and the Space Shuttle Discovery in 2009.

More Area Attractions & Services

  • 8 mile(s) from Amarillo Botanical Garden, experience the sights, sounds and floral fragrances of the Mary E. Bivins Conservatory; an indoor tropical garden bursting with a collection of unique and exotic plants. Explore four acres of seasonal outdoor themed plantings such as fragrance, butterfly, Japanese and xeric gardens. Don’t miss this truly one-of-a-kind oasis of lush landscaped gardens in the middle of the Texas Panhandle. Special events, classes, exhibits and rental facility also available.
  • 5 mile(s) from Amarillo Little Theatre, is a large, professionally staffed community theatre which is also among the oldest, continuously operating theatres in the country. The Amarillo Little Theatre produces nine shows each season in two distinctive venues. The ALT Main stage, which features more traditional theatre work geared for mainstream audiences, is at 2019 Civic Circle. The ALT Adventure Space is a smaller, more intimate venue featuring a more eclectic, contemporary repertoire. It is located at 2751 Civic Circle. Call for ticket prices.
  • 5 mile(s) from Amarillo Opera, is a professional regional opera company producing a wide variety of standard and adventurous operatic and musical theater. The company produces two main stage operas along with an educational opera celebrating Black History Month, a celebration of Latino/Hispanic music and the annual Summer Youth Musical each season in the acoustically acclaimed Globe-News Center for the Performing Arts in downtown Amarillo.
  • 4 mile(s) from Amarillo Symphony, delighting audiences since 1924, the Amarillo Symphony plays to sell-out crowds at the Globe-News Center for the Performing Arts, one of the nation's best acoustically-designed performance halls. The season includes seven full symphony performances, each featuring a professional guest artist. Also featured is a series by the renowned Harrington String Quartet and concerts by the Amarillo Youth Symphony. The Amarillo Symphony now has new administrative offices- stop by for a visit.
  • 4 mile(s) from Globe-News Center Arts, new in 2006, the Globe-News Center is a world-class performing arts palace featuring a 1,300 seat auditorium and a soaring, multi-tiered lobby. Public and professional consensus is the acoustics in the hall are outstanding. It is home to the opera, symphony and ballet and a variety of special events and concerts. The center is located in downtown Amarillo on Buchanan St., as part of the Amarillo Civic Center complex.
  • 7 mile(s) from Amarillo Zoo, where more than imaginations run wild! The zoo is a place to share the wonders of the animal world with kids of all ages. The beautiful 15-acre site is located in Thompson Park, just north of downtown, and features over 60 species. The zoo is open seveb days a week from 9:30 a.m. to 5:00 p.m.. It is closed New Year's Day, Martin Luther King Day, Thanksgiving and Christmas.
  • 2.00 mile(s) from Splash Amarillo, Amarillo's only water park with lots of creature comforts for the family. Enjoy zero gravity on the Sidewinder (one of a handful in the world), a large wave pool, lazy river, two speed slides, three serpentine slides and a big kiddie pool. Park is open from 12:00 p.m. to 7:00 p.m., Monday-Saturday, and 12 p.m. to 6:00 p.m. on Sunday, weather permitting. Plenty of covered areas with tables, arcade, gift shop (now serving alcohol), concession stand, sand volleyball courts and two horseshoe pits.
  • 2.00 mile(s) from Amarillo Civic Center, is one of the best, most versatile convention facilities in a city the size of Amarillo. It is located along Buchanan St. in downtown Amarillo with easy access to Interstate 40 and Interstate 27. The Amarillo Civic Center can host conventions, meetings, concerts, hockey games, rodeos and a variety of special events. The Center covers more than 340,000 square feet with a variety of facilities: a coliseum, exhibit halls, ballroom, auditorium and multi-purpose rooms. The newest part of the Amarillo Civic Center is the Globe-News Center for the Performing Arts, a 1,300 seat, world-class facility with near perfect acoustics that is home to the Amarillo Symphony, Amarillo Opera and Lone Star Ballet and a variety of other special concerts and events.
  • 3.00 mile(s) from Amarillo Art Museum, permanent and temporary exhibits housed in an Edward Durrell Stone designed three-story museum. Collections includes American Photography, Paintings, Prints, Drawings, and Sculptures; Price Collection of Asian Art; Tibetan Tsakli and Manuscript, and European paintings. Temporary exhibits have included grace Hartigan, Dante Maroni, Jasper Johns, and George Rouault.
  • 8 mile(s) from Amarillo Railroad Museum, see static display of unique railroad cars, including an actual White Train from the US Dept. of Energy. Also, a large HO display of the Santa Fe Railroad as it passed through the Texas Panhandle from Candian, Texas to Clovis, New Mexico is under construction. Also under development is the Phillip Pratt Memorial Garden Railway. Located on grounds of the former Amarillo Air Base in northeast Amarillo. From I-40 take Lakeside (Loop 335) north approximately two miles and exit onto US Highway. 60 eastbound. Travel approximately four miles and turn south onto I Avenue. The Museum is to the left. Open Thursday evenings from 7:30 p.m. to 9:30 p.m. and the second and fourth Saturdays of each month from 10:00 a.m. to 3:00 p.m. Admission is free and donations are appreciated.
  • 2 mile(s) from Route 66 Motor Speedway, where Motor-Sport enthusiasts can get a fix of racing action. Every Saturday night, April through September this up-to-date facility features 305 Sprints, Modified, Limited Modified, Street Stocks, Cyclones, and a Pony Stock division racing on a 3/8-mile, high-banked clay oval track.
  • 7.00 mile(s) from Texas Panhandle War Memorial, dedicated in 2003, this moving tribute honors all veterans from the greater Texas Panhandle, encompassing all conflicts from the Spanish-American War to the present. Located just north of the Randall County Courthouse Annex at 4111 S. Georgia at Interstate 27 in Amarillo. No admission fee!
  • 7.00 mile(s) from Wonderland Park, sixty years young, Wonderland Amusement Park is a great place for a family to relax and have fun for a reasonable price. Voted the 2009 Park of the Year by Amusement Today, Wonderland is home to the Texas Tornado, one of the top-rated, double-loop steel roller coasters in the nation, and to over 60 rides, attractions and miniature golf. Open weekends April through Labor Day and open weeknights from June 1 through the start of school in August.
  • 1 mile(s) from Kwahadi Museum, one of Amarillo's newest attractions, this facility features an extensive museum and a dance performance theater. The building mimics the design of an Indian Pueblo, and the exterior glows a beautiful pink in the sunset. Included is the Thomas Mails collection of Native American culture. Also on display are the fine bronze castings of Tom Knapp, the Cunningham Navajo Rug Collection, the Perry Null Game Animal Exhibit, and the Bob and Sally Jones Indigenous Birds of the Plains display.
  • 9 mile(s) from Cadillac Ranch, the world's only! Ten Cadillac’s buried nose-down in a field at the same angle as the Cheops Pyramid.
  • 7.00 mile(s) from Ross Rogers Golf Course, is located in Thompson Park north of downtown Amarillo. The Wild horse Course is consistently rated among the region's best public courses. And the new Mustang Course has opened for play this season. Mustang has been re-designed and re-constructed from the Old Course at Ross Rogers and has larger tees and greens, wider fairways, better bunkers and a larger lake. Both courses are great challenges and great values for all skill levels.
  • 8.00 mile(s) from Medical district
  • 8.00 mile(s) from The RV Museum, welcome to the RV Museum at Jack Sisemore Traveland. The Sisemore’s began collecting and restoring unusual vintage RV’s over 25 years ago and have built a museum to house their collection. These include the Flexible Bus from the movie RV, the first Itasca motor home ever built, and the oldest Fleetwood in existence. And many other RV’s from the 1930's through the 1970's. Step back in time, reminisce and enjoy the progression of the RV industry from its inception till now. Just walk in the main showroom and tell the friendly staff you want to see the RV Museum. They will point the way. The museum is free and is open Monday – Saturday, 9:00 a.m to 5:00 p.m.
  • 3 mile(s) from Amarillo Bulls, start their third season in the North American Hockey League, a 26-team league stretching from Alaska to Texas featuring top 16-20 year- old players aspiring to play collegiate and/or professional hockey. The league is the backbone of development for top-flight US hockey talent. Last season, the Bulls were champs of the league's Southern Division!
  • 15 mile(s) from Maxwell's Pumpkin Farm, a great fall activity for visitors and local families. Season runs from September. 22 through October 28. Activities include a giant maze, obstacle course, hayrides, pumpkin picking and a whole lot more. The farm is about halfway between Amarillo and Canyon. Exit I-27 at McCormick Road and turn east to Bell Street. Turn left on Bell and the farm entrance will be at the second set of red pipe gates on the left!
  • 8 mile(s) from Midnight Rodeo, approaching 25 years in Amarillo, the city has adopted Midnight Rodeo as its own. Easily the largest honky-tonk in the Texas panhandle
  • 14.00 mile(s) from Rock Island Rail Trail, nearly four miles of improved hike and bike trail from 7th & Crocket near downtown Amarillo to Coulter Dr. near the medical center. It is ideal for walking, running, biking or exercising a pet. The trail is named for the Rock Island Line, the famed railroad that operated along this trail in the early 1900s.
  • 14.00 mile(s) from West Texas University
  • 27.00 mile(s) from Palo Duro Canyon
  • 38.00 mile(s) from Lake Meredith

Nearby Restaurants

  • 3.00 mile(s) from The Big Texan® Steak Ranc, Bar/Lounge, Steak House, Open for: breakfast, lunch, The Big Texan provides a free limo service for any guest staying in any hotel in Amarillo Texas. Shuttle service starts at 5 p.m. and ends at 9 p.m. Just let the desk clerk know what time you would like to be picked up and we will be glad to set it up for you.
  • 1 mile(s) from El Tejavan, Full Service, Mexican, Open for: breakfast, lunch, dinner, From humble beginnings as a convenience store nearly 20 years ago to opening two full-service dining establishments now located along the I-40 corridor in Amarillo, Texas, El Tejavan is celebrated as the Panhandle’s destination for true Mexican cuisine!
  • 2.00 mile(s) from Coyote Bluff, Bar/Lounge, American, Open for: lunch, Hours are: Tuesday - Saturday 11 a.m. to 2:30 p.m. and 5 p.m. to 10 p.m. Closed on Sunday and Monday.
  • 3.20 mile(s) from Cracker Barrel®, Bar/Lounge, American, Open for: breakfast, lunch, Hours are: Sunday - Thursday 6 a.m. to 10 p.m. and Friday - Saturday 6 a.m. to 11 p.m.
  • 4 mile(s) from Buffalo Wild Wings, Bar/Lounge, American, Open for: lunch, dinner, Really, all you need to know “About Us” is these three things: Wings. Beer. Sports.™ Why do those three things matter to us so much? Because that’s what our fans want, and that’s what we’re all about—making our fans happy.
  • 8 mile(s) from Hoffbrau Steaks, Bar/Lounge, Steak House, Open for: lunch, dinner, Sun to Wed: 11am to 9pm Thurs to Sat: 11am to 10pm
  • 8 mile(s) from Pacific Rim, Buffet, Pacific Rim, Open for: lunch, dinner, Monday:-closed for lunch- Delivery $3.00 no minimum
  • 7 mile(s) from 575 Pizzeria, Full Service, Indian, Open for: lunch, dinner, Ranked #1 of 419 restaurants in Amarillo
  • 6 mile(s) from Golden Light Cafe, Bar/Lounge, American, Open for: lunch, dinner, The GoldenLight Cafe is the oldest restaurant in Amarillo and perhaps the oldest restaurant continuously operating in the same location anywhere on Old Route 66.
  • 8 mile(s) from Tyler's Barbecue, Full Service, American, Open for: lunch, dinner, Open Tuesday - Saturday 11 am to 8 pm or Until We Sell Out! Closed Sunday and Monday
  • 7 mile(s) from Macaroni Joes, Full Service, American, Open for: lunch, dinner, Lunch: Monday-Friday 11-2 Dinner: Monday-Friday 5-10 Saturday 5-10
  • 8 mile(s) from Malcolm's Ice Cream, Ice Cream/Dessert, American, Open for: lunch, dinner, Malcolm's is a classic, hometown favorite.
  • 6 mile(s) from Crush, Bar/Lounge, American, Open for: lunch, dinner, Outstanding wine cellar and light, fresh lunch and dinner menus in a great location in the middle of downtown. Outside tables and banquet space in addition to main seating area.

Best Western Santa Fe

Enjoy your stay with us even more by checking out some of the most popular area points of interest in or near Amarillo. Chase the links to explore the local region even more.

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